2012年11月20日火曜日

心臓領域の悪液質とサルコペニア

心臓領域の悪液質とサルコペニアの研究のミニレビュー論文を紹介します。

Coats AJ. Research on cachexia, sarcopenia and skeletal muscle in cardiology. J Cachexia Sarcopenia Muscle. 2012 Nov 16. [Epub ahead of print]

抄録しか読めていませんが、過去3年間の肥満パラドックス、原因、治療に関するミニレビュー論文のようです。がん、COPD、慢性腎不全、慢性肝不全の悪液質でも研究が進んでいるようです。心筋のサルコペニアに関する研究も増えてほしいですね。

Abstract

BACKGROUND:

The awareness of cardiac cachexia, i.e. involuntary weight loss in patients with underlying cardiovascular disease, has increased over the last two decades.

METHODS AND RESULTS:

This mini-review looks at recent research in the cardiovascular literature that is relevant to the areas of interest of the Journal of Cachexia, Sarcopenia and Muscle. It identifies significant research in the last 3 years on the obesity paradox, the causes and effects of skeletal muscle wasting, animal models of cachexia and emerging treatment ideas in cardiac cachexia.

CONCLUSIONS:

Assuming a similar literature in the fields of cancer, chronic obstructive pulmonary disease, chronic renal failure and chronic liver failure, the emergence of cachexia as a vibrant area of clinical and experimental research seems assured.

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