サルコペニアのコンセンサス論文その3

4月に2回紹介したESPENなどヨーロッパでのサルコペニアのコンセンサス論文ですが、下記のサイトで無料で全文を入手できます。

http://ageing.oxfordjournals.org/cgi/reprint/afq034v2

Sarcopenia: European consensus on definition and diagnosis
Report of the European Working Group on Sarcopenia in Older People
Alfonso J. Cruz-Jentoft et al.
Age and Ageing, doi:10.1093/ageing/afq034

コンセンサスの論文なので、エビデンスレベルとしては決して高いとは言えません。しかし、この論文のコンセンサスが、今後のサルコペニアの定義と診断、そして研究のベースになると私は考えています。

リハ栄養やサルコペニアに関心のある方に、ぜひ全文を読んでいただきたいと思います。サルコペニアのメカニズムの図、分類（原発性、二次性）、キーポイントを英語のままですが、改めて紹介します。

サルコペニアの分類
Primary sarcopenia
Age-related sarcopenia No other cause evident except ageing

Secondary sarcopenia
①Activity-related sarcopenia
Can result from bed rest, sedentary lifestyle, deconditioning or zero-gravity conditions

②Disease-related sarcopenia
Associated with advanced organ failure (heart, lung, liver, kidney, brain), inflammatory disease, malignancy or endocrine disease

③Nutrition-related sarcopenia
Results from inadequate dietary intake of energy and/or protein, as with malabsorption, gastrointestinal disorders or use of medications that cause anorexia

この論文のキーポイント
・Age-related sarcopenia is common and has huge personal and financial costs.

・This paper presents a clinical definition and consensus diagnostic criteria for sarcopenia, as developed by the European Working Group on Sarcopenia in Older People (EWGSOP) and endorsed by four participating professional medical societies.

・The overall goal was to compile a set of tools that would promote recognition and treatment of age-related sarcopenia in practice and also encourage conduct of well-designed research studies of its causes and consequences.